Vwc2l Gene Summary [Rat]
Predicted to be involved in negative regulation of BMP signaling pathway. Predicted to act upstream of or within positive regulation of neuron differentiation. Predicted to be located in synapse. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in extracellular space. Orthologous to human VWC2L (von Willebrand factor C domain containing 2 like). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Vwc2l |
| Official Name | von Willebrand factor C domain containing 2 like [Source:RGD Symbol;Acc:1565501] |
| Ensembl ID | ENSRNOG00000027400 |
| Bio databases IDs | |
| Aliases | von Willebrand factor C domain containing 2 like |
| Synonyms | A830006F12Rik, Brl, Brorin-l, LOC402117, RGD1565501, von Willebrand factor C domain containing 2 like, von Willebrand factor C domain-containing protein 2-like |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Vwc2l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- von Willebrand factor type C domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Vwc2l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of BMP signaling pathway
- positive regulation of neuron differentiation
Cellular Component
Where in the cell the gene product is active
- alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
- extracellular space
- synapse
Molecular Function
What the gene product does at the molecular level
- protein binding