Znhit6 Gene Summary [Rat]

Predicted to enable ATPase binding activity; TFIID-class transcription factor complex binding activity; and identical protein binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); protein-containing complex assembly; and snoRNA localization. Predicted to be part of pre-snoRNP complex. Predicted to be active in nucleus. Orthologous to human ZNHIT6 (zinc finger HIT-type containing 6). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Znhit6
Official Name
zinc finger, HIT-type containing 6 [Source:RGD Symbol;Acc:1308723]
Ensembl ID
ENSRNOG00000030049
Bio databases IDs NCBI: 292160 Ensembl: ENSRNOG00000030049
Aliases zinc finger, HIT-type containing 6
Synonyms 2410019A14Rik, BCD1, BREAST CANCER ANTIGEN NY-BR-75, C1orf181, NY-BR-75, RGD1308723, zinc finger, HIT type 6, zinc finger HIT-type containing 6, zinc finger, HIT-type containing 6
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Znhit6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ATPase binding
  • zinc finger HIT (zf-HIT) domain
  • binding protein
  • enzyme binding
  • transcription factor binding
  • protein binding
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ischemic stroke
  • neurodevelopmental disorder
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Znhit6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • snoRNA localization
  • box C/D snoRNP assembly
  • protein oligomerization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • extracellular vesicular exosome
  • pre-snoRNP complex

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • metal ion binding
  • TFIID-class transcription factor binding
  • enzyme binding
  • ATPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.