Hbg1 Gene Summary [Rat]
Predicted to enable several functions, including heme binding activity; hemoglobin alpha binding activity; and oxygen binding activity. Predicted to contribute to haptoglobin binding activity and peroxidase activity. Predicted to be involved in hydrogen peroxide catabolic process. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Human ortholog(s) of this gene implicated in delta beta-thalassemia and sickle cell anemia. Orthologous to human HBG1 (hemoglobin subunit gamma 1) and HBG2 (hemoglobin subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hbg1 |
| Official Name | hemoglobin subunit gamma 1 [Source:RGD Symbol;Acc:620306] |
| Ensembl ID | ENSRNOG00000030879 |
| Bio databases IDs | |
| Aliases | hemoglobin subunit gamma 1 |
| Synonyms | betaH1, Beta h1 globin, Embryonic (β h1) globin, Glnb2, haemoglobin subunit gamma 1, haemoglobin subunit γ 1, haemoglobin Z, beta-like embryonic chain, haemoglobin Z, β-like embryonic chain, Hbb-y, Hbbz, Hbe1, Hbg1, hemoglobin subunit gamma 1, hemoglobin subunit γ 1, hemoglobin Z, beta-like embryonic chain, hemoglobin Z, β-like embryonic chain, β h1 globin |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hbg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Globin
- oxygen transporter
- binding protein
- Globin-like protein superfamily
- heme binding
- hemoglobin binding
- transporter
Pathways
Biological processes and signaling networks where the Hbg1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown