Crygd Gene Summary [Rat]
A structural constituent of eye lens. Involved in lens fiber cell differentiation and response to peptide hormone. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in cataract 4 multiple types and cataract 7. Orthologous to human CRYGD (crystallin gamma D). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Crygd |
| Official Name | crystallin, gamma D [Source:RGD Symbol;Acc:2422] |
| Ensembl ID | ENSRNOG00000032219 |
| Bio databases IDs | |
| Aliases | crystallin, gamma D |
| Synonyms | Aey4, Cryg-1, Cryg4, crystallin, gamma D, crystallin, γ D, DGcry-1, Len, Lop12, γ D crystallin |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Crygd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of eye lens
- Peptidase inhibitor family I36
- Beta/Gamma crystallin
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus