Cenpi Gene Summary [Rat]
Involved in follicle-stimulating hormone signaling pathway. Predicted to be located in kinetochore and nuclear body. Predicted to be part of inner kinetochore. Orthologous to human CENPI (centromere protein I). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cenpi |
| Official Name | centromere protein I [Source:RGD Symbol;Acc:2631] |
| Ensembl ID | ENSRNOG00000033335 |
| Bio databases IDs | |
| Aliases | centromere protein I |
| Synonyms | centromere protein I, FSHPRH1, LRPR1, RNALRP |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cenpi often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CTF3_NTD_HEAT
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- organismal death
- breast cancer
- small cell lung cancer
- glioma formation
- glioma
role in cell
- cell death
- spindle checkpoint
- ionizing radiation sensitivity
- misalignment
- niraparib sensitivity
- misalignment in
- mitosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nuclear bodies
- kinetochores
- centromeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cenpi gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sex differentiation
- mitotic sister chromatid segregation
- chromosome segregation
- CenH3-containing nucleosome assembly at centromere
Cellular Component
Where in the cell the gene product is active
- nucleus
- condensed chromosome inner kinetochore
- nuclear body
- cytosol
- kinetochore
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding