Etfbkmt Gene Summary [Rat]

Predicted to enable heat shock protein binding activity and protein-lysine N-methyltransferase activity. Predicted to be involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase and peptidyl-lysine trimethylation. Predicted to be located in mitochondrion. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrial matrix. Orthologous to human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Etfbkmt
Official Name
electron transfer flavoprotein subunit beta lysine methyltransferase [Source:RGD Symbol;Acc:735147]
Ensembl ID
ENSRNOG00000036918
Bio databases IDs NCBI: 316976 Ensembl: ENSRNOG00000036918
Aliases electron transfer flavoprotein subunit beta lysine methyltransferase
Synonyms 4833442J19Rik, AI256744, C12orf72, electron transfer flavoprotein beta subunit lysine methyltransferase, electron transfer flavoprotein subunit beta lysine methyltransferase, electron transfer flavoprotein subunit β lysine methyltransferase, electron transfer flavoprotein β subunit lysine methyltransferase, METTL20
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Etfbkmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein-lysine N-methyltransferase
  • heat shock protein binding
  • enzyme
  • methyltransferase domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
regulated by
  • beta-estradiol
  • EIF6
disease
  • squamous cell lung cancer
  • lung squamous cell carcinoma
role in cell
  • trimethylation in
  • dimethylation in
  • methylation in
  • consumption in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Etfbkmt gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • peptidyl-lysine trimethylation
  • methylation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • cytoplasm
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • heat shock protein binding
  • protein-lysine N-methyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.