ETFBKMT Gene Summary [Human]
Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of electron transfer activity; negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase; and peptidyl-lysine trimethylation. Located in mitochondrial matrix. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ETFBKMT |
| Official Name | electron transfer flavoprotein subunit beta lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:28739] |
| Ensembl ID | ENSG00000139160 |
| Bio databases IDs | |
| Aliases | electron transfer flavoprotein subunit beta lysine methyltransferase |
| Synonyms | 4833442J19Rik, AI256744, C12orf72, electron transfer flavoprotein beta subunit lysine methyltransferase, electron transfer flavoprotein subunit beta lysine methyltransferase, electron transfer flavoprotein subunit β lysine methyltransferase, electron transfer flavoprotein β subunit lysine methyltransferase, METTL20 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ETFBKMT often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-lysine N-methyltransferase
- heat shock protein binding
- enzyme
- methyltransferase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ETFBKMT gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-lysine trimethylation
- methylation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- cytoplasm
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- heat shock protein binding
- protein-lysine N-methyltransferase activity