Etfbkmt Gene Summary [Mouse]
Enables protein-lysine N-methyltransferase activity. Involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase and peptidyl-lysine trimethylation. Predicted to be located in cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrial matrix. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; respiratory system; and thymus. Orthologous to human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Etfbkmt |
| Official Name | electron transfer flavoprotein beta subunit lysine methyltransferase [Source:MGI Symbol;Acc:MGI:2443575] |
| Ensembl ID | ENSMUSG00000039958 |
| Bio databases IDs | |
| Aliases | electron transfer flavoprotein beta subunit lysine methyltransferase |
| Synonyms | 4833442J19Rik, AI256744, C12orf72, electron transfer flavoprotein beta subunit lysine methyltransferase, electron transfer flavoprotein subunit beta lysine methyltransferase, electron transfer flavoprotein subunit β lysine methyltransferase, electron transfer flavoprotein β subunit lysine methyltransferase, METTL20 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Etfbkmt often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-lysine N-methyltransferase
- heat shock protein binding
- enzyme
- methyltransferase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Etfbkmt gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-lysine trimethylation
- methylation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- cytoplasm
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- heat shock protein binding
- protein-lysine N-methyltransferase activity