Dnal1 Gene Summary [Rat]
Predicted to enable alpha-tubulin binding activity and dynein heavy chain binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be located in cell projection and microtubule. Predicted to be part of dynein complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 16. Orthologous to human DNAL1 (dynein axonemal light chain 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Dnal1 |
| Official Name | dynein, axonemal, light chain 1 [Source:RGD Symbol;Acc:1591349] |
| Ensembl ID | ENSRNOG00000042333 |
| Bio databases IDs | |
| Aliases | dynein, axonemal, light chain 1 |
| Synonyms | 1700010H15Rik, C14orf168, CILD16, Dnalc1, dynein axonemal light chain 1, dynein, axonemal, light chain 1, E330027P08Rik, LC1, LOC679326 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dnal1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- leucine-rich repeat
- protein phosphatase 1 regulatory subunit 42
- alpha-tubulin binding
- Leucine rich repeat
- protein binding
- dynein heavy chain binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dnal1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- outer dynein arm assembly
Cellular Component
Where in the cell the gene product is active
- outer dynein arm
- cytoplasm
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- alpha-tubulin binding
- dynein heavy chain binding