Dnal1 Gene Summary [Mouse]
Predicted to enable alpha-tubulin binding activity and dynein heavy chain binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be located in microtubule. Predicted to be part of outer dynein arm. Predicted to be active in cytoplasm. Is expressed in brain ependyma; node; and upper respiratory tract epithelium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 16. Orthologous to human DNAL1 (dynein axonemal light chain 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Dnal1 |
| Official Name | dynein, axonemal, light chain 1 [Source:MGI Symbol;Acc:MGI:1921462] |
| Ensembl ID | ENSMUSG00000042523 |
| Bio databases IDs | |
| Aliases | dynein, axonemal, light chain 1 |
| Synonyms | 1700010H15Rik, C14orf168, CILD16, Dnalc1, dynein axonemal light chain 1, dynein, axonemal, light chain 1, E330027P08Rik, LC1, LOC679326 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dnal1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- leucine-rich repeat
- protein phosphatase 1 regulatory subunit 42
- alpha-tubulin binding
- Leucine rich repeat
- protein binding
- dynein heavy chain binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dnal1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- outer dynein arm assembly
Cellular Component
Where in the cell the gene product is active
- outer dynein arm
- cytoplasm
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- alpha-tubulin binding
- dynein heavy chain binding