Nudt10 Gene Summary [Rat]

Predicted to enable diphosphoinositol-polyphosphate diphosphatase activity. Predicted to be located in cytosol. Orthologous to several human genes including NUDT11 (nudix hydrolase 11). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nudt10
Official Name
nudix (nucleoside diphosphate linked moiety X)-type motif 10 [Source:RGD Symbol;Acc:1564763]
Ensembl ID
ENSRNOG00000046053
Bio databases IDs NCBI: 680248 NCBI: 367747 Ensembl: ENSRNOG00000046053
Aliases nudix (nucleoside diphosphate linked moiety X)-type motif 10
Synonyms APS1, ASP1, DIPP3, Dipp3a, DIPP3b, DIPP3beta, hDIPP3beta, LOC100912928, LOC683238, nudix hydrolase 11, Nudt10
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nudt10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NUDIX domain
  • diphosphoinositol-polyphosphate diphosphatase
  • phosphatase
  • protein binding
  • NUDIX hydrolase superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epileptic seizure
  • infection by HIV-1
regulated by
regulates
  • 1-diphosphoinositol pentakisphosphate
  • P1,P6-di(adenosine-5') hexaphosphate
  • bis(1,4)-diphosphoinositol tetrakisphosphate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nudt10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • diphosphoinositol polyphosphate metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • endopolyphosphatase activity
  • protein binding
  • bis(5'-adenosyl)-hexaphosphatase activity
  • metal ion binding
  • diphosphoinositol-polyphosphate diphosphatase activity
  • bis(5'-adenosyl)-pentaphosphatase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.