NUDT11 Gene Summary [Human]
NUDT11 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 [PubMed 12105228]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | NUDT11 |
| Official Name | nudix hydrolase 11 [Source:HGNC Symbol;Acc:HGNC:18011] |
| Ensembl ID | ENSG00000196368 |
| Bio databases IDs | |
| Aliases | nudix hydrolase 11 |
| Synonyms | APS1, ASP1, DIPP3, Dipp3a, DIPP3b, DIPP3beta, hDIPP3beta, LOC100912928, LOC683238, nudix hydrolase 11, Nudt10 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NUDT11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NUDIX domain
- diphosphoinositol-polyphosphate diphosphatase
- phosphatase
- protein binding
- NUDIX hydrolase superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NUDT11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- diphosphoinositol polyphosphate metabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- endopolyphosphatase activity
- protein binding
- bis(5'-adenosyl)-hexaphosphatase activity
- metal ion binding
- diphosphoinositol-polyphosphate diphosphatase activity
- bis(5'-adenosyl)-pentaphosphatase activity