Mtrf1 Gene Summary [Rat]

Predicted to enable translation release factor activity, codon specific. Predicted to be involved in mitochondrial translational termination. Predicted to be active in mitochondrion. Orthologous to human MTRF1 (mitochondrial translation release factor 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mtrf1
Official Name
mitochondrial translation release factor 1 [Source:RGD Symbol;Acc:1584329]
Ensembl ID
ENSRNOG00000047106
Bio databases IDs NCBI: 686234 Ensembl: ENSRNOG00000047106
Aliases mitochondrial translation release factor 1
Synonyms A830062K05Rik, mitochondrial translational release factor 1, mitochondrial translation release factor 1, MRF1, MTTRF1, RF1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mtrf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PCRF domain
  • This domain is found in peptide chain release factors
  • peptide chain release factor 2
  • peptide chain release factor 1
  • translation release factor activity, codon specific
  • translation release factor
  • Outer membrane protein (OmpH-like)
  • Effector-associated domain 9
  • RF-1 domain
  • translation regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mtrf1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translational termination

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • translation release factor activity
  • translation release factor activity, codon specific

Gene-Specific Assays for Results You Can Trust

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