Mtrf1 Gene Summary [Mouse]
Predicted to enable translation release factor activity, codon specific. Predicted to be involved in mitochondrial translational termination. Located in mitochondrion. Orthologous to human MTRF1 (mitochondrial translation release factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtrf1 |
| Official Name | mitochondrial translational release factor 1 [Source:MGI Symbol;Acc:MGI:2384815] |
| Ensembl ID | ENSMUSG00000022022 |
| Bio databases IDs | |
| Aliases | mitochondrial translational release factor 1 |
| Synonyms | A830062K05Rik, mitochondrial translational release factor 1, mitochondrial translation release factor 1, MRF1, MTTRF1, RF1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mtrf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PCRF domain
- This domain is found in peptide chain release factors
- peptide chain release factor 2
- peptide chain release factor 1
- translation release factor activity, codon specific
- translation release factor
- Outer membrane protein (OmpH-like)
- Effector-associated domain 9
- RF-1 domain
- translation regulator
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mtrf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translational termination
Cellular Component
Where in the cell the gene product is active
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- translation release factor activity
- translation release factor activity, codon specific