Details

Type
Protein Coding
Official Symbol
Magea8
Official Name
melanoma antigen, family A, 8 [Source:RGD Symbol;Acc:1565778]
Ensembl ID
ENSRNOG00000048840
Bio databases IDs NCBI: 302638 Ensembl: ENSRNOG00000048840
Aliases melanoma antigen, family A, 8
Synonyms Magea1, Magea2, Magea5, Magea6, Magea8, MAGE family member A1, MAGE family member A2, MAGE family member A3, MAGE family member A5, MAGE family member A6, MAGE family member A8, RGD1565778
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Magea8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • Melanoma associated antigen family N terminal
  • MAGE homology domain
  • protease binding
  • transcription factor binding
  • histone deacetylase binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • beta-estradiol
  • FGF7
  • Large T Antigen
regulates
  • TP53
  • DNA promoter
  • DNA endogenous promoter
  • histone H3
role in cell
  • expression in
  • methylation in
  • acetylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • Endoplasmic Reticulum
  • cytosol
  • nucleoplasm
  • nuclear bodies
  • PML nuclear bodies

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.