Nktr Gene Summary [Rat]

Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human NKTR (natural killer cell triggering receptor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nktr
Official Name
natural killer cell triggering receptor [Source:RGD Symbol;Acc:2321593]
Ensembl ID
ENSRNOG00000049128
Bio databases IDs NCBI: 100364165 Ensembl: ENSRNOG00000049128
Aliases natural killer cell triggering receptor
Synonyms 5330401F18RIK, CypNK, D9Wsu172e, natural killer cell triggering receptor, Natural Killer Tumor-Recognition Sequence, Natural Killer tumour-Recognition Sequence, p104
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nktr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • peptidylprolyl isomerase
  • Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
  • cyclophilin
  • cyclosporin A binding
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • squamous-cell carcinoma
  • squamous cell cancer
  • senile lentigo
regulated by
  • NEF
  • dexamethasone
  • aphidicolin
  • Immunoglobulin
  • CD247
  • B lymphocytes
  • AGTR1
  • AGT
  • Large T Antigen
  • CD3 (complex)
role in cell
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nktr gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein peptidyl-prolyl isomerization
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • mitochondrion
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • cyclosporin A binding
  • peptidyl-prolyl cis-trans isomerase activity

Gene-Specific Assays for Results You Can Trust

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