Naif1 Gene Summary [Rat]
Predicted to be involved in negative regulation of cell growth and regulation of mitochondrial membrane permeability involved in apoptotic process. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Orthologous to human NAIF1 (nuclear apoptosis inducing factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Naif1 |
| Official Name | nuclear apoptosis inducing factor 1 [Source:RGD Symbol;Acc:1597546] |
| Ensembl ID | ENSRNOG00000050204 |
| Bio databases IDs | |
| Aliases | nuclear apoptosis inducing factor 1 |
| Synonyms | 2310007O20Rik, 4933440H19Rik, bA379C10.2, C9orf90, nuclear apoptosis inducing factor 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Naif1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GT1, myb-like, SANT family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Naif1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell growth
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrion
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding