NAIF1 Gene Summary [Human]
Involved in negative regulation of cell growth and regulation of mitochondrial membrane permeability involved in apoptotic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | NAIF1 |
| Official Name | nuclear apoptosis inducing factor 1 [Source:HGNC Symbol;Acc:HGNC:25446] |
| Ensembl ID | ENSG00000171169 |
| Bio databases IDs | |
| Aliases | nuclear apoptosis inducing factor 1, nuclear apoptosis-inducing factor 1 |
| Synonyms | 2310007O20Rik, 4933440H19Rik, bA379C10.2, C9orf90, nuclear apoptosis inducing factor 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAIF1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GT1, myb-like, SANT family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAIF1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell growth
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrion
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding