Adgre4 Gene Summary [Rat]
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human ADGRE4P (adhesion G protein-coupled receptor E4, pseudogene). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adgre4 |
| Official Name | adhesion G protein-coupled receptor E4 [Source:RGD Symbol;Acc:1359641] |
| Ensembl ID | ENSRNOG00000050325 |
| Bio databases IDs | |
| Aliases | adhesion G protein-coupled receptor E4 |
| Synonyms | Adgre4p, adhesion G protein-coupled receptor E4, D17Ertd479e, Egf-tm7, Emr4, Emr4p, Fire, Gpr127 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Adgre4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 7 transmembrane receptor (Secretin family)
- GPCR proteolysis site, GPS, motif
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Adgre4 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane