Adgre4 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within epidermal growth factor receptor signaling pathway. Located in cell surface. Is expressed in alimentary system; gonad; and metanephros. Orthologous to human ADGRE4P (adhesion G protein-coupled receptor E4, pseudogene). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Adgre4
Official Name
adhesion G protein-coupled receptor E4 [Source:MGI Symbol;Acc:MGI:1196464]
Ensembl ID
ENSMUSG00000032915
Bio databases IDs NCBI: 52614 Ensembl: ENSMUSG00000032915
Aliases adhesion G protein-coupled receptor E4
Synonyms Adgre4p, adhesion G protein-coupled receptor E4, D17Ertd479e, Egf-tm7, Emr4, Emr4p, Fire, Gpr127
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adgre4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 7 transmembrane receptor (Secretin family)
  • GPCR proteolysis site, GPS, motif
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Adgre4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • cellular membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.