Spty2d1 Gene Summary [Rat]

Enables DNA binding activity and histone binding activity. Involved in nucleosome organization; regulation of chromatin assembly; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Spty2d1
Official Name
SPT2 chromatin protein domain containing 1 [Source:RGD Symbol;Acc:2319415]
Ensembl ID
ENSRNOG00000050806
Bio databases IDs NCBI: 100365259 Ensembl: ENSRNOG00000050806
Aliases SPT2 chromatin protein domain containing 1
Synonyms 5830435K17RIK, AU019572, FLJ39441, P16H6, Spt2, SPT2 chromatin protein domain containing 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Spty2d1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • histone binding
  • SPT2 chromatin protein
  • enzyme binding
  • protein binding
  • DNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • human immunodeficiency virus I infection
regulated by
  • CREB1
  • CREM
  • bicuculline
  • dalfampridine
  • kainic acid
role in cell
  • formation
  • assembly
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Spty2d1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • heterochromatin assembly
  • transcription from RNA polymerase I promoter
  • regulation of transcription, DNA-dependent
  • nucleosome assembly

Cellular Component

Where in the cell the gene product is active
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • RNA polymerase I core binding
  • histone binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.