Spty2d1 Gene Summary [Mouse]
Predicted to enable several functions, including RNA polymerase I core binding activity; histone binding activity; and histone chaperone activity. Predicted to be involved in chromatin remodeling; regulation of DNA-templated transcription; and transcription by RNA polymerase I. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Orthologous to human SPTY2D1 (SPT2 chromatin protein domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Spty2d1 |
| Official Name | SPT2 chromatin protein domain containing 1 [Source:MGI Symbol;Acc:MGI:2142062] |
| Ensembl ID | ENSMUSG00000049516 |
| Bio databases IDs | |
| Aliases | SPT2 chromatin protein domain containing 1 |
| Synonyms | 5830435K17RIK, AU019572, FLJ39441, P16H6, Spt2, SPT2 chromatin protein domain containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Spty2d1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone binding
- SPT2 chromatin protein
- enzyme binding
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Spty2d1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heterochromatin assembly
- transcription from RNA polymerase I promoter
- regulation of transcription, DNA-dependent
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA polymerase I core binding
- histone binding