LOC103690371 Gene Summary [Rat]

Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including MAGEA10 (MAGE family member A10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
LOC103690371
Official Name
melanoma-associated antigen 10-like [Source:RGD Symbol;Acc:9361810]
Ensembl ID
ENSRNOG00000052773
Bio databases IDs NCBI: 103690371 NCBI: 293832 Ensembl: ENSRNOG00000052773
Aliases melanoma-associated antigen 10-like
Synonyms CT1.10, MAGE10, MAGE family member A10, RGD1563693
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc103690371 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin protein ligase binding
  • Melanoma associated antigen family N terminal
  • MAGE homology domain
  • transcription factor binding
  • histone deacetylase binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • organismal death
  • esophageal adenocarcinoma
  • esophageal carcinoma formation
  • neuroblastoma
  • neuroblastoma formation
  • MYCN amplification negative neuroblastoma
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm
  • PML nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc103690371 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • histone deacetylase binding

Gene-Specific Assays for Results You Can Trust

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