Rps4x Gene Summary [Rat]
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in response to ethanol. Located in ribosome. Orthologous to human RPS4X (ribosomal protein S4 X-linked). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps4x |
| Official Name | ribosomal protein S4, X-linked [Source:RGD Symbol;Acc:2324318] |
| Ensembl ID | ENSRNOG00000003201 |
| Bio databases IDs | |
| Aliases | ribosomal protein S4, X-linked |
| Synonyms | CCG2, DXS306, eS4, Ribosomal protein s4, ribosomal protein S4 X-linked, ribosomal protein S4, X-linked, RPS4, Rps4-1, RS4X, S4, SCAR, SCR10 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rps4x often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- P domain
- structural constituent of ribosome
- S4
- 6-pyruvoyl-tetrahydropterin synthase related domain (membrane protein)
- RS4NT (NUC023) domain
- S4 domain
- S4 RNA-binding domain
- Ribosomal family S4e
- protein binding
- 40S ribosomal protein S4 C-terminus
- A domain
Pathways
Biological processes and signaling networks where the Rps4x gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- myelodysplastic syndrome
- Klinefelter syndrome
- depressive disorder
- acute myeloid leukemia
- Turner syndrome
- myocardial infarction
- Parkinson disease
regulates
- Actin
- RNR
role in cell
- proliferation
- cell death
- translation in
- processing in
- CSN5i-3 sensitivity
- cell survival
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pre-ribosome
- cytoplasmic ribonucleoprotein granule
- cellular membrane
- ribosome
- Nucleus
- cytosol
- spliceosomes
- nucleoplasm
- nucleoli
- nuclear envelope
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rps4x gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of translation
- cytoplasmic translation
- ribosomal small subunit biogenesis
- positive regulation of cell proliferation
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- synapse
- ribosome
- nucleolus
- nucleoplasm
- extracellular vesicular exosome
- focal adhesion
- membrane
- cytosol
- small ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- structural constituent of ribosome
- rRNA binding