Sltm Gene Summary [Rat]

Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of mRNA processing and regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body. Predicted to be active in nucleus. Orthologous to human SLTM (SAFB like transcription modulator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sltm
Official Name
SAFB-like, transcription modulator [Source:RGD Symbol;Acc:1307526]
Ensembl ID
ENSRNOG00000054446
Bio databases IDs NCBI: 315792 Ensembl: ENSRNOG00000054446
Aliases SAFB-like, transcription modulator
Synonyms 5730455C01Rik, 5730555F13RIK, 9130215G10Rik, Met, RGD1307526, SAFB like transcription modulator, SAFB-like, transcription modulator
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sltm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • SAP motif
  • RNA recognition motif
  • SAP domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • major depression
  • Jeune syndrome
  • Asperger syndrome
regulated by
  • DAP3
  • sulforafan
  • Jurkat E6.1 cells
  • phosphate
role in cell
  • growth
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • interchromatin granule cluster fractions
  • nucleoplasm
  • nuclear bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sltm gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of mRNA processing
  • apoptotic process
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear body
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • sequence-specific DNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.