Stath Gene Summary [Rat]
Predicted to be involved in defense response to bacterium. Predicted to be located in extracellular region. Orthologous to human HTN1 (histatin 1); HTN3 (histatin 3); and STATH (statherin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Stath |
| Official Name | statherin [Source:RGD Symbol;Acc:1589974] |
| Ensembl ID | ENSRNOG00000054677 |
| Bio databases IDs | |
| Aliases | statherin |
| Synonyms | LOC686440, Statherin, STR |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Stath often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Statherin
- protein binding
- hydroxyapatite binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Extracellular Space
- membrane surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Stath gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of bone mineralization
- saliva secretion
- ossification
- defense response to bacterium
- biomineral tissue development
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- hydroxyapatite binding
- protein binding
- extracellular matrix constituent, lubricant activity
- structural constituent of tooth enamel