Mocs2 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to contribute to molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in nuclear speck. Predicted to be part of molybdopterin synthase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Orthologous to human MOCS2 (molybdenum cofactor synthesis 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mocs2 |
| Official Name | molybdenum cofactor synthesis 2 [Source:RGD Symbol;Acc:1359477] |
| Ensembl ID | ENSRNOG00000056325 |
| Bio databases IDs | |
| Aliases | molybdenum cofactor synthesis 2 |
| Synonyms | MCBPE, MOCO1, MOCODB, MOCS2A, MOCS2B, molybdenum cofactor synthesis 2, Molydopterin converting factor subunit 2, MPTS |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mocs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mo-molybdopterin synthase
- molybdopterin-synthase adenylyltransferase
- MoaE
- Ubl1_cv_Nsp3_N-like
- molybdopterin synthase
- enzyme
- protein binding
- identical protein binding
Pathways
Biological processes and signaling networks where the Mocs2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mocs2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Mo-molybdopterin cofactor biosynthetic process
- molybdopterin cofactor biosynthetic process
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- nucleotide binding
- protein binding
- Mo-molybdopterin synthase activity