Fcsk Gene Summary [Rat]

Predicted to enable fucokinase activity. Involved in response to dopamine. Orthologous to human FCSK (fucose kinase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fcsk
Official Name
fucose kinase [Source:RGD Symbol;Acc:1307000]
Ensembl ID
ENSRNOG00000059453
Bio databases IDs NCBI: 307848 Ensembl: ENSRNOG00000059453
Aliases fucose kinase
Synonyms 1110046B12Rik, CDGF2, fucose kinase, FUK, L-Fucokinase
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fcsk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • fucokinase
  • L-fucokinase
  • GHMP kinases N terminal domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • congenital disorder of glycosylation with defective fucosylation 2
  • congenital disorder of glycosylation with defective fucosylation
regulated by
  • L-fucose
  • lipopolysaccharide
  • HNF1A
  • HNF4A
  • dextran sulfate
regulates
  • carbohydrate
  • GDP fucose

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fcsk gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • GDP-L-fucose salvage
  • carbohydrate phosphorylation

Cellular Component

Where in the cell the gene product is active
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • fucokinase activity

Gene-Specific Assays for Results You Can Trust

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