Fcsk Gene Summary [Mouse]
Enables fucokinase activity. Involved in GDP-L-fucose salvage and carbohydrate phosphorylation. Predicted to be active in cytosol. Is expressed in axial skeleton and cranium. Orthologous to human FCSK (fucose kinase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Fcsk |
| Official Name | fucose kinase [Source:MGI Symbol;Acc:MGI:1916071] |
| Ensembl ID | ENSMUSG00000033703 |
| Bio databases IDs | |
| Aliases | fucose kinase |
| Synonyms | 1110046B12Rik, CDGF2, fucose kinase, FUK, L-Fucokinase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fcsk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- fucokinase
- L-fucokinase
- GHMP kinases N terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fcsk gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- GDP-L-fucose salvage
- carbohydrate phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- fucokinase activity