Cdc42se1 Gene Summary [Rat]

Predicted to enable small GTPase binding activity. Predicted to be involved in phagocytosis; regulation of Rho protein signal transduction; and regulation of cell shape. Predicted to be located in cell junction. Predicted to be active in plasma membrane. Orthologous to human CDC42SE1 (CDC42 small effector 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cdc42se1
Official Name
CDC42 small effector 1 [Source:RGD Symbol;Acc:1561700]
Ensembl ID
ENSRNOG00000060538
Bio databases IDs NCBI: 499672 Ensembl: ENSRNOG00000060538
Aliases CDC42 small effector 1
Synonyms 1300002M12Rik, CDC42 small effector 1, Cdcse1, SCIP1, SPEC1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdc42se1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CRIB
  • GTPase inhibitor
  • protein binding

Pathways

Biological processes and signaling networks where the Cdc42se1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • osteoporosis
  • metabolic syndrome X
regulated by
regulates
  • F Actin
  • reporter gene
  • JNK
  • MAPK8
role in cell
  • blebbing
  • ruffling

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell junction
  • Cytoplasm
  • cell cortex

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cdc42se1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of cell shape
  • regulation of Rho protein signal transduction
  • signal transduction
  • phagocytosis

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • cytoplasm
  • cell junction
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • GTPase inhibitor activity
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.