Npy4r Gene Summary [Rat]

Enables pancreatic polypeptide receptor activity and peptide hormone binding activity. Involved in G protein-coupled receptor signaling pathway. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Npy4r
Official Name
neuropeptide Y receptor Y4 [Source:RGD Symbol;Acc:61864]
Ensembl ID
ENSRNOG00000061026
Bio databases IDs NCBI: 29471 Ensembl: ENSRNOG00000061026
Aliases neuropeptide Y receptor Y4
Synonyms CH17 360D51, CH17-360D5.1, neuropeptide Y receptor Y4, neuropeptide Y receptor Y4-2, NPY4-R, PP1, PPYR1
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Npy4r often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • peptide YY receptor
  • pancreatic polypeptide receptor
  • peptide binding
  • Cholecystokinin A receptor, N-terminal
  • 7 transmembrane receptor (rhodopsin family)
  • seven-transmembrane G protein-coupled receptor superfamily
  • polypeptide hormone binding

Pathways

Biological processes and signaling networks where the Npy4r gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • progesterone
  • olanzapine
regulates
  • cyclic AMP

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • membrane fraction
  • cellular membrane
  • basal lamina
  • axons

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Npy4r gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neuropeptide signaling pathway
  • G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • neuron projection
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • neuropeptide binding
  • pancreatic polypeptide receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.