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GeneGlobe ID: JHS-3002Z | Cat. No.: | QIAseq RNA Fusion XP Panels

QIAseq RNA Fusion XP Pan Heme Panel

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Product Specification

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

Target List

Covers specific sides of specific exons of the targeted genes based on the Human GRCh38 genome build.Analyzes the expression of the targeted genes.Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build.

Leukemia
Acute Leukemia of Ambiguous Lineage​
ABL1AFF1BCRCT45A2ETV6EWSR1GPHNKMT2AMLLT10MN1NUP214PBX1SETTCF3ZNF384
Acute Lymphoblastic Leukemia (ALL)​
ABL1ABL2ACTN4AFDNAFF1AFF3AFF4AGGF1ANLNASNSATF7IPAUTS2BCL11BBCL9BCRBTBD18CASC5CREBBPCRLF2CSF1RDDX3XEBF1ELLELNEML1EP300EPOREPS15ESRRBETV6EWSR1FGFR1FGFR1OPFLT3FOXO4FOXP1FRYLGAS7GPHNHLFHNRNPUL1INPP5DJAK2KMT2AKMT2ELNP1MAML2MEF2DMLLT1MLLT10MLLT3MN1MNX1MYBMYCNCOA2NOTCH1NUP214NUP98P2RY8PAG1PAX5PBX1PCM1PDGFRBPICALMPMLPRDM16RAP1GDS1RARARCSD1RUNX1SALL2SETSFPQSPI1SSBP2STILSTMN1TAF15TAL1TCF3TCF7TET1TYK2USP9XZBTB16ZCCHC7ZMIZ1ZMYM2ZNF384ZNF521ATMBRAFCDKN2ACREBBPCSF3RDNM2EGFRFBXW7GATA2HRASMAP2K1MLH1PAX5PDGFRAPTENSMARCB1
Acute Myeloid Leukemia (AML)​
ABI1ABI2ABL1AFDNAFF1AFF4ALKANLNARHGAP26ARHGEF12BCORBCRCASC5CBFA2T3CBFBCBLCCDC88CCEP170BCHD1CHIC2CREBBPDAB2IPDDX10DEKDHHDIAPH2ELLEP300EPS15ERGETV6FGFR1FIP1L1FLNAFNBP1FOXO3FOXO4FRYLFUSGAS7GATA1GLIS2GPHNHAUS1HOXA9HOXC11HOXC13HOXD13IRF2BP2JAK2KAT6AKDM5AKIAA1524KMT2ALASP1LNP1LPPLYNMAML2MECOMMKL1MLF1MLLT1MLLT10MLLT11MLLT3MLLT6MN1MNX1MYBMYH11MYO1FNCKIPSDNCOA2NF1NPM1NSD1NTRK3NUMA1NUP214NUP98PAN3PBX1PCM1PDGFRAPDGFRBPDS5APHF23PICALMPMLPRDM16PRRX1PSIP1PSMA2PTPRRRANBP2RARARBM15RHEBL1RPL22RPN1RUNX1RUNX1T1SARNPSEPT2SEPT5SEPT6SEPT9SETSH3GL1SORBS2STAT5BTAF15TCF3TET1TFGTOP1TOP3ATRIP11TYK2UBA2USP42WHSC1L1WTIPZBTB16ZFYVE19ZNF384ASXL1ATMBCORBRAFCDKN2ACHEK2CREBBPCSF3RDAXXDNM2FLT3GATA2IDH1IDH2JAK1JAK3KITKMT2DKRASMAP2K1MPLMYCNRASPBRM1PDGFRAPPM1DPTENPTPN11RAD21RETRUNX1SMARCB1SRSF2U2AF1WT1
Acute Myelomonocytic Leukemia (AMML)​
FLNAHOXD13NUP98
B-Cell Acute Lymphoblastic Leukemia (B-ALL)​
ABL1ACTN4AFF1AFF3AFF4ATF7IPBCRBTBD18CRLF2EPS15ERGESRRBETV6EWSR1FUSGAS7JAK2KMT2AMAPRE1MLLT1NUP214P2RY8PAX5PBX1PCM1RUNX1SETSSBP2TCF3USP9XZNF384ZNF521
Blast Phase Chronic Myeloid Leukemia​
ABL1BCRETV6JAK2
Chronic Eosinophilic Leukemia​
ACSL6TNIP1
Chronic Lymphocytic Leukemia (CLL)​
MYCNOTCH1BRAFCHEK2CSF3RMAP2K1TERT
Chronic Myeloid Leukemia (CML)​
ABL1BCRCCDC88CETV6HOXA11HOXA13JAK2MECOMMN1NDE1NUP98PCM1PDGFRBRUNX1ABL1CDKN2ACREBBPCSF3RFBXW7GATA2
Chronic Myelomonocytic Leukemia (CMML)​
CREBBPELLETV6KMT2AMN1CSF3RHRASSRSF2
Myelodysplastic Syndromes (MDS)​
ABL1ACTN4ALKCASC5CREBBPDEKERGETV6FRYLFUSHOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1NDE1NPM1NUP214NUP98PCM1PDGFRBPRDM16PTPRRRANBP2RUNX1RUNX1T1TOP1CDKN2ACSF3RETNK1GNASHRASRAD21SETBP1SRSF2U2AF1XPO1ZRSR2
Myeloproliferative Neoplasms​
ABL1ACSL6BCRETV6FGFR1FGFR1OPFIP1L1FLT3HOXA9HOXD13JAK2LYNMECOMMLF1MN1NPM1NUP98PDGFRBPRKG2PSIP1RARARUNX1TNIP1ZMYM2ABL1ASXL1JAK2JAK3KRASMPLNRASSETBP1SF3B1SH2B3SRSF2
T-Cell Acute Lymphoblastic Leukemia (T-ALL)​
ABL1AFDNAGGF1ASNSBCL11BBCRCASC5DDX3XETV6JAK2KMT2AKMT2EMLLT1MLLT10NOTCH1NUP214PBX1RUNX1SALL2SETSPI1STILSTMN1TAL1TCF3TCF7
Other Leukemias​
BCL11BIKZF2IKZF3IRF2BP2MYCNPM1PDCD1LG2SETD2TYK2
Chronic Neutrophilic Leukemia (CNL)​
CSF3R
Multiple Myeloma​
ATMBRAFCDKN2AEGFRFBXW7HRASMYCPTENSMARCB1
Myeloid Malignancies​
CBLCBLBDNMT3AEZH2
Myelofibrosis​
CHEK2IDH1IDH2SRSF2
Other Myeloid Neoplasms​
BRAFCDKN2ACUX1FBXW7HRASMYD88PTENSTAT3
Lymphoma
Acute Lymphoblastic Lymphomas​
BCL11BCREBBPEBF1KMT2AMLLT10MYCP2RY8PRDM16STIL
Anaplastic Large Cell Lymphomas​
ADGRG7ALKATICCLTCMSNMYCNPM1TFGTPM3TPM4ALKCDKN2ADNMT3ANRASSTAT3
Angioimmunoblastic T Cell Lymphomas​
CD28CTLA4FIP1L1PDGFRAALKAPCARID1AASXL1ATMBRAFCDKN2ACREBBPCTNNB1DNMT3AEZH2FBXW7IDH2JAK1JAK3KITKMT2DKRASMED12PLCG1RHOASTAT3WT1XPO1ZFHX3
Burkitt Lymphomas​
BCL6MYCPBX1TCF3APCARID1AATMCD79BCDKN2ACREBBPFBXW7HLA-AID3KRASMYCMYD88NRASPAX5PIK3CAPIK3R1PTENRHOASRSF2
Diffuse Large B Cell Lymphomas (DLBCL)​
ALKBCL11ABCL6CCND3CIITACLTCIGLL5LPPMAPK13MYCNPM1PIM1RELSQSTM1TBL1XR1TOMM40TP63ZCCHC7ALKAMER1APCARID1AASXL1ATMB2MBCL2BCORBRAFBTKCD79BCDKN2ACNOT3CREBBPCTNNB1CXCR4DNMT3AEZH2FBXW7HLA-AID3IDH2IRS4JAK1JAK3KITKMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASNSD2PAX5PIK3CAPIK3R1PLCG1POT1PPM1DPTENRGS7RHOASF3B1SMOSRSF2STAT3STAT5BSTAT6TERTTRRAPWT1XPO1ZFHX3ZNF479
Follicular Lymphomas​
AFF3BCL2BCL6CIITAMYCTBL1XR1TP63AMER1ARID1AATMB2MBCL2BCORBRAFBTKCD79BCDKN2ACREBBPCXCR4DNMT3AEZH2FBXW7ID3IDH2KMT2DMAP2K1MED12MYD88NOTCH2NRASPIK3R1PPM1DPTENRGS7RHOASRSF2STAT6ZMYM3
Granulocytic Sarcomas​
RUNX1RUNX1T1
Hodgkin Lymphomas​
ALKCIITAJAK2NPM1SEC31AARID1AASXL1B2MBCORCDKN2ADNMT3AEZH2NFKBIENRASPAX5PIK3R1PPM1DSF3B1
Inflammatory Myofibroblastic Tumors​
ALKDCTN1
Lymphoblastic Lymphomas​
BCRCRLF2EPORETV6FGFR1NOTCH1PBX1PDGFRBRARAZCCHC7
Lymphoblastic T Cell Lymphomas​
BCRETV6FGFR1FIP1L1LYNPDGFRA
Mantle Cell Lymphomas​
CCND3MYCARID1AASXL1ATMB2MBCORBRAFBTKCDKN2ACREBBPDNMT3AIDH2KMT2DKRASMED12NCOR1NFKBIENOTCH2NRASNSD2PAX5POT1PPM1DPTENSTAT3TERTZFHX3
Mediastinal Large B Cell Lymphomas (MLBL)​
CIITAPDCD1LG2
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas​
BCL6BIRC3CCND3MALT1MYCMYD88NOTCH2
Peripheral T Cell Lymphomas​
ALKETV6FGFR3IKZF2ITKMYO1FNPM1S100A7SYKTBL1XR1THAP4TP63VAV1ALKARID1AASXL1ATMCDKN2ACTNNB1DNMT3AIDH2IRS4KITKMT2DKRASMAP2K1MSNNRASPLCG1PTENRGS7RHOASTAT3STAT5BTRRAPXPO1ZFHX3ZNF479
Precursor T Cell Lymphoblastic Lymphomas​
ABL1JAK2NUP214PCM1SETCTNNB1FBXW7NRASWT1
T Cell Lymphomas​
ATXN2LBCL11BFGFR1IKZF2JAK2
Other Lymphomas​
BCL6BIRC3CBFBCCND1CCND3CDK6CHIC2DEKDUSP22EIF4A1KMT2AMALT1MKL1MLF1MLLT10MYCNFKB2PICALMPRDM16
AIDS-Related Lymphomas​
EZH2
B Cell Lymphomas​
ARID1AATMB2MBCL2BCORBRAFCD79BCDKN2ACREBBPCTNNB1CXCR4DNMT3AEZH2JAK3KITKMT2DMAP2K1MYD88PIK3CAPPM1DPTENRHOASTAT3
Small Lymphocytic Lymphomas​
ALKAPCARID1AASXL1ATMBCL2BCORBRAFBTKCD79BCDKN2ACNOT3CREBBPCXCR4DNMT3AFBXW7GNASIRS4JAK1JAK3KITKMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASPAX5PIK3CAPIK3R1PLCG1POT1PPM1DPTENRGS7SF3B1STAT5BSTAT6TERTTRRAPXPO1ZFHX3ZMYM3ZNF479
Cutaneous T Cell Lymphomas​
KRASPTEN
Diffuse Red Pulp Small B Cell Lymphomas​
MYD88NOTCH2
Enteropathy-Type T Cell Lymphomas​
STAT5B
Gamma-Delta T Cell Lymphomas​
STAT3STAT5B
Hepatosplenic T Cell Lymphomas​
STAT3STAT5B
Lymphoplasmacytic Lymphomas​
ARID1ABTKCD79BCXCR4DNMT3AMYD88
Marginal Zone Lymphomas​
AMER1ARID1AASXL1ATMBRAFCD79BCREBBPCXCR4DNMT3AEZH2FBXW7GNASJAK3KITKMT2DMAP2K1MYD88NFKBIENOTCH2PIK3R1RHOASRSF2TRRAPXPO1
Mycosis Fungoides (Sezary Syndrome)​
AMER1ARID1AATMBCORCDKN2ADNMT3AJAK1JAK3KMT2DKRASNCOR1NRASPIK3CAPLCG1POT1PTENSTAT3STAT5B
NK-T Cell Lymphomas​
ALKAMER1APCARID1AASXL1ATMB2MBCORBRAFCTNNB1DNMT3AEZH2FBXW7HLA-AJAK1JAK3KITKMT2DKRASMED12NCOR1NOTCH2NRASPOT1RGS7RHOASMOSTAT3STAT5BWT1XPO1ZFHX3
Primary Central Nervous System Lymphomas​
B2MBCL2CD79BCDKN2ACXCR4DNMT3AHLA-AJAK3KITKRASMYD88NOTCH2POT1STAT3STAT5BTERTTRRAPWT1
Primary Effusion Lymphomas​
CDKN2APTEN
Myelodysplastic Syndromes (MDS)
ABL1ACTN4ALKCASC5CREBBPDEKDIAPH2ERGETV6FGFR1FRYLFUSGOT1HOXA11HOXA13HOXD13JAK2KMT2ALNP1MAML2MECOMMLF1MN1MNX1MYH11NDE1NPM1NUP214NUP98PAN3PCM1PDGFRBPRDM16PSMA2PTPRRRANBP2RUNX1RUNX1T1SEPT9SYKTOP1ZMYM2
Myeloproliferative Neoplasms
ABL1ACSL6BCRCNTRLETV6FGFR1FGFR1OPFIP1L1FLT3FOXP1HOXA9HOXD13JAK2KANK1LYNMECOMMLF1MN1NPM1NUP98PCM1PDGFRAPDGFRBPRKG2PSIP1RARARUNX1TNIP1
Other Hematological Malignancies
Eosinophilia​
ETV6FOXP1LYNPDGFRA
Langerhans Cell Histiocytosis​
NTRK3PLEKHA6
Plasma Cell Myelomas​
ABL1BCR
Polycythemia Vera​
GTF2H3
Severe Thrombocythemia​
KANK1PDGFRB
Other Myeloid Neoplasms
KLF2PTK2BSEMA6A
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFREML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
General Leukemia Markers
ANPEPCD19CD200CD33CD34CD38CR2FOXM1FOXO3HOXA9ITGA6KITMS4A1RUNX1
Leukemia Subtype Markers
Acute Lymphoblastic Leukemia (ALL)​
ANPEPBTG1CASP8AP2CD19CD1ACD2CD22CD33CD5CD7CD79ACD8ACR2ETV6HLA-DRAHLA-DRB1IL2RAJUNKITLMO1LMO2LYL1MEIS1MMEMS4A1MYCPBX1PTPRCRB1VEGFAWT1
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
BTG1CD300ACD72CD79ACD79BCD86CDKN2ACDKN2BCRLF2EBF1ETV6HOXA9IKZF1PAX5RB1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BTKCD27CD4KCNN4LMO1LMO2LYL1MMP9RUNX1SERPINI1TAL1THBS1TLX1TLX3VPREB3
Acute Myeloid Leukemia (AML)​
ADGRE5ASS1BAALCBCL11BBIRC5CD200CD300ACD44CD86CD96CD99CLEC12AERGFCGR2AFLT3HAVCR2IL2RAJUNKITKLF4LEF1MECOMMEIS1MMP9NPM1PTPRCTHBS1VEGFAWT1
Chronic Lymphocytic Leukemia (CLL)​
ABCA6AIM2AKT1BAXBCL2BIRC2BTKCD19CD200CD24CD27CD5CD79BCXCR4IL7ITGA4ITGAMJUNKCNN4LAIR1LEF1MCL1MMP9MS4A1ROR1SERPINI1SOX11THBS1TNFTTNVEGFAVPREB3WNT3
Chronic Myeloid Leukemia (CML)​
AURKAAURKBIL2RAJUNKITPTCH1PTPRC
Other Leukemia Subtypes​
CD72IL2RASPI1
Leukemia Stem Cell & Proliferation Markers
ADGRG1BAALCBMI1CD33CD34CD44CD47CD96CD99CLEC12ACXCL12CXCR4ERGFCGR2AHAVCR2IL2RAIL3RAKITKLF4LAIR1LIN28AMYCPOU5F1PTPRCSOX2THY1WT1
Possible Prognostic Significance
Indicator of Clinical Outcome in Leukemia​
AURKBBAALCBIRC5ERGFOXO3GATA2MECOMMEIS1RUNX1SPI1WT1
Acute Lymphoblastic Leukemia (ALL)​
ABCB1AKT1ANPEPBIRC5CD33CD3DCD44FLT3HOXA9IKZF1JUNMMEMYCPAX5SMYD2
B Cell Acute Lymphoblastic Leukemia (B-ALL)​
ANPEPCD33CRLF2JUNMS4A1
T Cell Acute Lymphoblastic Leukemia (T-ALL)​
BCL11BBMI1LMO1LMO2LYL1MYCTAL1TLX1TLX3
Acute Myeloid Leukemia (AML)​
ABCB1ANGPT2BAALCBCL2BIRC2BIRC5BMI1CCNA1CD200CD34CD4CD44CD47CD96CLEC12ACXCL12CXCR4ERGGATA2HAVCR2HGFIL2RAIL3RAKLF4LEF1MECOMMEIS1MN1MYCRUNX1SOX11SOX2SPI1WT1XIAP
Chronic Lymphocytic Leukemia (CLL)​
ABCA6ANGPT2BCL2CD24CD38CD69ITGA4KCNN4LAIR1LPLMS4A1MYCNOTCH1ROR1SOX11TTNUGT2B17VPREB3WNT3ZAP70
Chronic Myeloid Leukemia (CML)​
AURKAAURKBLIN28AMCL1PTCH1
Chemotherapy Resistance Related​
AKT1AURKBBAALCBCL2BIRC2CD274CD274CD44CD47ERGHLA-DRAHLA-DRB1IL3RAMCL1MYCXIAP
Hypoxia & Oxidative Stress Related​
ANGPT2VEGFA
Treatment Target or Treatment Indicator​
ASS1BMI1CASP8AP2CD33CD47CD69CD96CDC25ACDKN2ACDKN2BCLEC12ACXCR4FLT3FOXM1FOXO3HAVCR2IL3RAITGAMKLF4LMO2MS4A1MYCPTCH1SERPINI1SMARCA4TAL1ZAP70
Associated with Invasiveness or Infiltration into Central Nervous System​
CXCL12CXCR4ZAP70
Minimal Residual Disease​
ADGRE5BAALCBCL2CD19CD200CD24CD300ACD44CD47CD69CD72CD79BCD86CD99CLEC12AHAVCR2IL2RAIL3RAITGA6NPM1PBX1WT1
Mechanistic Role in Pathogenesis
BCL11BBCL2BMI1ERGFOXM1GATA2HOXA9LMO2LPLMEIS1NOTCH1PAX5SPI1TAL1TLX1TLX3TNFVEGFAWT1
Expression Altered due to Genetic Alterations
Acute Lymphoblastic Leukemia (ALL)​
AHI1BCL11ABCL2BCL9BRD4CCND2CEBPACEBPBCEBPDCEBPECEBPGCRLF2EPORETV6HOXA1ID4IGF2BP1IL3IRF4IRS4LCKLHX4LMO1LMO2LYL1MYBMYCNKX2-5NOTCH1OLIG2TAL2TLX1TLX3
Acute Myeloid Leukemia (AML)​
MECOMNKX2-5RANBP17TCL1ATLX3
Lymphoma​
BCL10BCL2BCL3BCL6BCL9CCND1CCND2CCND3CD44CDK6ERVW-1FCGR2BFCRL4FOXP1GPR34IRF4KDSRMALT1MTCP1MUC1MYCNBEAP1NFKB2PAX5PRDM16
Myelomas​
FGFR3MAFMAFBNSD2
Other Leukemia Subtypes & Other Genetic Alterations​
BAALCBCL11BCRLF2ERGKITLMO1LPLNPM1TAL1ZAP70

Product Resources

icon_0041_download-s Download Target List
icon_0041_download-s Detailed Target List for each Analyte
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Resources

Safety Data Sheets (1)
Kit Handbooks (2)
QIAseq RNA Fusion XP Panel Handbook Version 2
PDF (1MB)
QIAseq RNA Fusion XP Panel Handbook
PDF (2MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis
Introducing the QIAseq RNA Fusion XP Pan Heme Panel, a cutting-edge addition to our QIAseq RNA Fusion XP Panels lineup, specifically designed for {{application}} applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq RNA Fusion XP Pan Heme Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting {{application}}, or any other sophisticated analyses, this product from our QIAseq RNA Fusion XP Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq RNA Fusion XP Pan Heme Panel and elevate your work to new heights.
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