Target List
Acute Lymphoblastic Leukemia (ALL)
ASXL2, ATM, BRAF, CALR, CDKN2A (P16INK4A), CREBBP (CBP), CRLF2 (TSLPR), CSF3R (GM-CSFR), CTCF, DNM2, EGFR (ERBB1), EP300, FBXW7, GATA2, HNRNPK, HRAS, IKZF3, IL7R, KDM6A, KDR (VEGFR3), KMT2C, LRRC4, MAP2K1, MLH1, MSH2, MSH6, NOTCH1, NTRK3, PAX5, PDGFRA, PMS2, PRAMEF2, PTEN, RELN, SMARCB1
Acute Myeloid Leukemia (AML)
ANKRD26, ASXL1, ATM, BCOR, BCORL1, BIRC3 (c-IAP2), BRAF, C17orf97, CALR, CARD11, CBLC, CDKN2A (P16INK4A), CEBPA, CHEK2 (RAD53), CREBBP (CBP), CSF1R, CSF3R (GM-CSFR), CTCF, DAXX, DDX41, DNM2, DNMT1, ELANE, EP300, FLRT2, FLT3, GATA1, GATA2, HNRNPK, IDH1, IDH2, IKZF1, IL7R, JAK1, JAK3, KDM6A, KDR (VEGFR3), KIT (CD117), KMT2A, KMT2C, KRAS, LRRC4, MAP2K1, MPL, MSH6, MYC, NBN, NOTCH1, NPM1, NRAS, NSD1, NTRK3, OR13H1, OR8B12, P2RY2, PCDHB1, PDGFRA, PHF6, PRAMEF2, PRPF8, PTEN, PTPN11, RAD21, RUNX1 (AML1), SF1, SF3A1, SMARCB1, SMC1A, SMC3, SRP72, SRSF2, STAG2, STXBP2, U2AF1, U2AF2, WT1
Chronic Lymphocytic Leukemia (CLL)
ADA, BIRC3 (c-IAP2), BLM, BRAF, CALR, CHEK2 (RAD53), CSF3R (GM-CSFR), KCNA4, KLHL6, KMT2C, MAP2K1, NBN, NPAT, NTRK3, OR13H1, OR8B12, PRAMEF2, SRP72, TAL1, TERT, TUBA3C, WAS, WRN
Chronic Myeloid Leukemia (CML)
ABL1, CALR, CDKN2A (P16INK4A), CEBPA, CREBBP (CBP), CSF1R, CSF3R (GM-CSFR), FBXW7, GATA2, KDM6A, MSH2, MSH6, RB1, SMC1A, TP53 (p53)
Chronic Myelomonocytic Leukemia (CMML)
CALR, CEBPA, CSF1R, CSF3R (GM-CSFR), HRAS, KMT2C, LUC7L2, SRSF2
Chronic Neutrophilic Leukemia (CNL)
CALR, CSF3R (GM-CSFR)
Multiple Myeloma
ATM, BCL6, BCR, BIRC3 (c-IAP2), BRAF, CDKN2A (P16INK4A), CEBPA, EGFR (ERBB1), FBXW7, GJB3, HRAS, KDM6A, MYC, NOTCH1, PTEN, SH2D1A, SMARCB1
Myelodysplastic Syndromes (MDS)
ATRX, CALR, CDKN2A (P16INK4A), CEBPA, CSF1R, CSF3R (GM-CSFR), EP300, ETNK1, GNAS, HRAS, KDM6A, KMT2A, KMT2C, RAD21, RB1, SETBP1, SF1, SF3A1, SMC3, SRSF2, STAG2, U2AF1, U2AF2, XPO1, ZRSR2
Myeloid Malignancies
CBL, CBLB, DNMT3A, EED, ETV6, EZH2, PRPF40B, SUZ12, TET2, TP53 (p53)
Myeloproliferative Neoplasm (MPN)
ABL1, ASXL1, CALR, CSF1R, JAK2, JAK3, KAT6A, KRAS, MPL, NF1, NRAS, RB1, SETBP1, SF3B1, SH2B3, SRSF2, STAG2
Myelofibrosis (MF)
CALR, CHEK2 (RAD53), IDH1, IDH2, CSF1R, SRSF2
Other Myeloid Neoplasms
BRAF, CDKN2A (P16INK4A), CEBPA, FBXW7, HRAS, IKZF3, KLHDC8B, KMT2C, MSH6, NTRK3, PTEN, SRP72, TPMT
Other Myeloid Neoplasm Genes
BRCA1, BRCA2, BRINP3, CUX1, FAM47A, FAS, KCNK13, MYD88, PML, PRF1, SAXO2, STAT3, TERC, TNFRSF13B