GeneGlobe ID: DHS-6600Z | Cat. No.: | QIAseq Targeted DNA Panels

QIAseq Targeted DNA Human Tumor Mutational Burden Panel

Kit containing ALL reagents (except indexes) for targeted DNA sequencing

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Product Specification

Target List

Oncogenes
ABL1, AKT1, AKT2, ALK, AR, BCL2, BRAF, CARD11, CBL, CDK4, CRKL, CRLF2 (TSLPR), CSF1R, CTNNB1, DNMT3A, EGFR (ERBB1), ERBB2 (HER-2, NEU), EZH2, FGFR2, FGFR3, FLT3, FOXL2, GATA2, GNA11, GNAQ, GNAS, H3-3A, H3C2, HRAS, IDH1, IDH2, IKBKE, JAK1, JAK2, JAK3, KIT (CD117), KRAS, MAP2K1, MED12, MET, MPL, MYD88, NFE2L2, NRAS, PDGFRA, PIK3CA (p110-alpha), PPP2R1A, PTPN11, REL, RET, SF3B1, SMO, SPOP, SRC, TSHR, U2AF1
Tumor Suppressor Genes
ACVR1B, AMER1, APC, ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATM, ATRX, AXIN1, B2M, BAP1, BARD1, BCOR, BRCA1, BRCA2, CDC73, CDH1 (E-Cadherin), CDKN2A (P16INK4A), CEBPA, CIC, CREBBP (CBP), CYLD, DAXX, EP300, FAT1, FBXW7, FLCN, FOXP1, FUBP1, GATA1, GATA3, HNF1A, KDM5C, KDM6A, KMT2C, KMT2D, MAP3K1 (MEKK1), MEN1, MLH1, NF1, NF2, NOTCH1, NOTCH2, NPM1, PAX5, PHF6, PIK3R1 (p85-ALPHA), PRDM1, PTCH1, PTEN, RB1, RNF43, RUNX1 (AML1), SMAD2 (MADH2), SMAD4 (MADH4), SMARCA4, SMARCB1, SOCS1, SOX9, STAG2, STK11 (LKB1), TET2, TNFAIP3, TP53 (p53), TSC1, TSC2, VHL, WT1, ZFHX3
Angiogenesis
AKT1, AKT2, AKT3, CTNNB1, ERBB2 (HER-2, NEU), FGFR2, FLT1 (VEGFR1), FLT4 (VEGFR2), GATA2, KDR (VEGFR3), NF1, NOTCH1, PIK3CA (p110-alpha), PTEN, PTGS2 (COX2), RUNX1 (AML1), TNFAIP3, VEGFA, VEGFD (VEGFD), VHL
Apoptosis
ABL1, ABL2 (ARG), AKT1, AKT2, AKT3, APC, ARAF, AXIN1, BCL2, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL6, BRAF, CASP8 (FLICE), CBL, CDKN1A (p21CIP1, WAF1), CDKN2A (P16INK4A), CTNNA1, CTNNB1, CYLD, DAXX, FAS, FLT3, FOXL2, GATA1, HGF, HRAS, MAP2K4 (MKK4, JNKK1), MCL1, MDM4, MYCN, NF1, NPM1, PIM1, PRKCI, PTEN, RAD21, RAD50, RAD51, RAF1, RB1, REL, SOX9, STK11 (LKB1), TNF, TNFAIP3, TP73, VHL, WT1
Cell Adhesion Molecules
ABL1, ABL2 (ARG), APC, CDH1 (E-Cadherin), CTNNB1, DDR2, EGFR (ERBB1), EPCAM, ERBB2 (HER-2, NEU), FAT1, GATA1, JAK2, KDR (VEGFR3), NF1, NF2, NOTCH1, PDGFRA, PTEN, PTGS2 (COX2), PTPN11, RAC1, RET, RHOA, SRC, TSC1
Cell Cycle
ABL1, ABL2 (ARG), AKT1, AKT2, AKT3, APC, ATR, BLM, BRD4, CCND1, CCND2, CCND3, CCNE1, CDC27, CDC73, CDK12, CDK4, CDK6, CDK8, CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2A (P16INK4A), CDKN2B (p15INK4b), CDKN2C (p18-INK4C), CHEK1, CHEK2 (RAD53), CREBBP (CBP), CUX1, CYLD, FBXW7, FGFR2, HRAS, MYC, NPM1, PIM1, PTEN, PTPRD, RAD21, RAD50, RAD51, RB1, RHEB, RHOA, SMARCA4, SMARCB1, SMC1A, SMC3, SOX2, SOX9, STAG2, STK11 (LKB1), TNFAIP3, TP53 (p53), TP53BP1, TSC1, WEE1, XPO1, ZFHX3
DNA Damage & Repair
ABL1, ABL2 (ARG), APC, ATM, ATR, ATRX, AXIN2, BRCA1, BRCA2, BRIP1, CDKN1A (p21CIP1, WAF1), CHEK1, CHEK2 (RAD53), EP300, EPCAM, ERCC1, ERCC2 (XPD), ERCC3 (XPB), ERCC4, ERCC5, EXO1, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, GADD45A, HERC1, HMGB1, HMGN1, LIG1, LIG3, MCM2, MCM3, MCM4, MCM5, MCM6, MCM7, MDM2, MEN1, MLH1, MLH3, MRE11, MSH2, MSH3, MSH4, MSH5, MSH6, MTOR, MUTYH, NBN, NPM1, PALB2, PARP1 (ADPRT1), PCNA, PIK3C2B, PMS1, PMS2, POLB, POLD1, POLD2, POLD3, POLD4, POLE, POLE4, PRKCG, PRKCZ, PRKDC, RAD17, RAD18, RAD21, RAD50, RAD51, RAD51C, RFC1, RFC2, RFC3, RFC4, RFC5, RNASEH2A, RPA1, RPA2, RPA3, RPA4, SETD2, SIRT1, SMC1A, SMC3, SSBP1, STK11 (LKB1), TDG, TP53 (p53), TP53BP1, TP73, TREX1, TRRAP, XRCC5
Epigenetics
ARID1A, ARID1B, ARID2, ARID5B, ASXL1, ASXL2, ATRX, AURKA, AURKB, BCOR, BCORL1, BRD4, CHD4, CTCF, DICER1, DNMT3A, DOT1L, EED, EZH2, FOXA1, H3-3A, H3C2, IKZF1, KAT6A, KDM5A, KDM5C, KDM6A, KMT2A, KMT2C, KMT2D, NCOR1, NSD1, PBRM1, PHF6, PRDM1, RARA, RUNX1T1, SMARCA4, SMARCB1, SPOP, SUZ12, TET2, TRRAP
Hypoxia Signaling
CREBBP (CBP), EP300, NF1, PDK1, SMAD4 (MADH4), VHL
Immune Response
ALK, B2M, BTK, CARD11, CD274 (PD-L1), CD274 (PD-L1), CD276, CD79A, CD79B, CREBBP (CBP), CRLF2 (TSLPR), CYLD, EP300, FAM46C, IL7R, IRF4, JAK1, JAK2, JAK3, MAP2K1, MAP2K2 (MEK2), MAP3K1 (MEKK1), MCL1, MYD88, NFKBIA (IκBα, MAD3), PAX5, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PTEN, PTPN11, REL, TNFAIP3, TNFRSF14, TP53 (p53)
Inflammatory Response
CEBPA, CSF1R, JAK2, MYD88, PTGS2 (COX2), REL
Metabolism
AKT1, AKT2, AKT3, ASXL2, FH, FLCN, IDH1, IDH2, MTOR, PDK1, PTGS2 (COX2), RICTOR, RPTOR, SDHA, SDHB, SDHC, SDHD, TNF, TSC2
RNA Splicing
DDX3X, QKI, RBM10, SF3B1, SMC1A, U2AF1
Signal Transduction
ACVR1B, AKT1, AKT2, AKT3, ALK, AMER1, APC, AXIN1, AXL, CBFB, CDKN1A (p21CIP1, WAF1), CNKSR1, CSF1R, CYLD, DDR2, DNER, EGFR (ERBB1), EPHA3, EPHA5, EPHA7, EPHB1, ERBB2 (HER-2, NEU), ERBB3, ERBB4, ERRFI1, EWSR1, FBXW7, FGF19, FGF3, FGF4, FGFBP1, FGFR1, FGFR2, FGFR3, FGFR4, FLT1 (VEGFR1), FLT3, FLT4 (VEGFR2), GABRA6, GATA2, GLI1, GNA11, GNA13, GNAQ, GNAS, GRIN2A, GSK3B, HGF, HNF1A, IGF1R, IGF2, IGF2R, IKBKE, INPP4B, IRF6, IRS2, JAK1, JAK2, JAK3, KDR (VEGFR3), KIT (CD117), KRAS, LMO1, LPAR2, MAP2K1, MAP2K2 (MEK2), MAP3K1 (MEKK1), MED12, MET, NF1, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PDGFRB, PIK3CA (p110-alpha), PIK3CB, PIK3CG, PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PLCG2, PPP2R1A, PRKAR1A, PRKCI, PTCH1, PTEN, PTPN11, RAF1, RASA1, RET, RIT1, RNF43, ROS1, SMAD2 (MADH2), SMAD3 (MADH3), SMAD4 (MADH4), SMO, SOCS1, SOS1, SOX17, SOX2, SPEN, SRC, STAT3, SUFU, SYK, TCF7L2, TGFBR2, TNF, TNKS (TIN1), TRRAP, TSC2, TSHR
Transcription Factors
AR, CEBPA, CIC, CUX1, ERG, ESR1 (ERα), ETV6, FBXW7, FOXA1, FOXL2, FOXP1, FUBP1, GATA1, GATA2, GATA3, GATA4, GATA6, GLI1, HNF1A, IRF4, IRF6, JUN, KEAP1, LZTR1, MEF2B, MEN1, MITF, MYB, MYC, MYCL, MYCN, MYOCD, NFE2L2, NKX2-1, PAX5, RB1, RUNX1 (AML1), SMAD2 (MADH2), SMAD3 (MADH3), SMAD4 (MADH4), SOX10, SOX17, SOX2, SOX9, TBX3, TCF7L2, TP53 (p53), TP73, WT1, ZFHX3, ZNF217
Ubiquitination
ASXL2, BAP1, BCOR, CDC27, CUL3, CUL4B, DAXX, MDM2, PRKN, RNF43
Unfolded Protein Response
HSP90AA1, NFE2L2, NPM1
Major Histocompatibility Complex Genes
B2M, HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G, MR1
Antigen Presentation
ABCB9, ACE2, CALR, CANX, CTSB, CTSL, CTSS, ERAP1, ERAP2, IDE, IFI30, LGMN, LNPEP, NPEPPS, NRD1, PDIA3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB1, PSMB10, PSMB11, PSMB2, PSMB3, PSMB4, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMC6, PSMD1, PSMD10, PSMD11, PSMD12, PSMD13, PSMD14, PSMD2, PSMD3, PSMD4, PSMD5, PSMD6, PSMD7, PSMD8, PSMD9, PSME1, PSME2, PSME3, PSME4, PSMF1, PSMG1, PSMG2, PSMG3, PSMG4, TAP1 (ABCB2), TAP2 (ABCB3), TAPBP, TAPBPL, TOP1, TPP2
Immune Checkpoint Molecules
VSIR, CD200, CD274 (PD-L1), CD274 (PD-L1), CD276, CD40 (TNFRSF5), CD40LG, CD48, CD70, CD80, CD86, ICOSLG, ITGAV, ITGB3, LGALS9, MICA, MICB, PDCD1LG2, TNFRSF14, TNFRSF9, TNFSF14, TNFSF18, TNFSF4 (OX40L), TNFSF9, VTCN1
Other Cancer-Related Genes
ALPK2, COL5A1, DIS3, DMD, FKBP9, KEL, LRP1B, MORC4, MUC17, TCP11L2, TERC, TERT, TOP1

Resources

Brochures & Guides (6)

Next-generation sequencing using QIAGEN’s QIAseq – a powerful tool for human identification


State-of-the-art technologies to fast-track and streamline NGS workflows
Advanced sample collection, automation and STR solutions for kinship testing
Safety Data Sheets (1)
Kit Handbooks (2)
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Illumina NGS systems
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Ion Torrent NGS systems
Certificates of Analysis (1)
Introducing the QIAseq Targeted DNA Human Tumor Mutational Burden Panel, a cutting-edge addition to our QIAseq Targeted DNA Panels lineup, specifically designed for NGS applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq Targeted DNA Human Tumor Mutational Burden Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting NGS, or any other sophisticated analyses, this product from our QIAseq Targeted DNA Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq Targeted DNA Human Tumor Mutational Burden Panel and elevate your work to new heights.