Target List
Covers all exons in all known transcripts of targeted genes based on the Human GRCh38 genome build
Adenocarcinomas
APCATMAXIN2BMPR1A (ALK3)BRAFBRCA1BRCA2CHEK2 (RAD53)EP300FLCNMLH1MLH3MSH2MSH3MSH6MUTYHNRASPALB2PMS1PMS2POLD1POLEPTENRNF43SMAD4 (MADH4)STK11 (LKB1)TGFBR2TP53 (p53)
Colorectal Cancer Susceptibility
CCND1GALNT12POLD1POLESMAD7
Familial Adenomatous Polyposis
APCMSH3MUTYHNTHL1POLD1POLE
Hereditary Mixed Polyposis Syndrome
BMPR1A (ALK3)GREM1
Hereditary Nonpolyposis
BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2
Hereditary Polyposis Syndrome
BMPR1A (ALK3)GREM1
Juvenile Polyposis Syndrome
BMPR1A (ALK3)SMAD4 (MADH4)
Lynch Syndrome
BRAFEPCAMMLH1MLH3MSH2MSH6PMS1PMS2TGFBR2
Metastatic Colorectal Cancers
ATMBRAFNRAS
Muir-Torre Syndrome
MLH1MSH2
Other Colorectal Cancer Genes
AURKABLMCDH1 (E-Cadherin)PKHD1PLA2G2ARB1RPS20SEMA4ATLR2XRCC2