GeneGlobe ID: UPHS-035Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human TGFß / BMP Signaling Pathway

QuantiNova LNA Probe PCR Focus Panel
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Product Specification

Target List
TGFβ Superfamily Ligands
Activins​
INHA, INHBA, INHBB
Bone Morphogenetic Proteins​
AMH, BMP1, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, GDF2 (BMP9), GDF3 (VGR-2), GDF5 (CDMP-1), GDF6, GDF7
Nodal​
NODAL
TGFβ Family Members​
TGFB1, TGFB2, TGFB3
Inhibitors & Cofactors of TGFβ Signaling​
BAMBI, CHRD, DCN, FST, LEFTY1, LTBP1, LTBP2, NOG, TGFBI, TGFBRAP1, TGIF1, THBS1 (TSP-1)
TGFβ Superfamily Receptors
Activin Receptors​
ACVR1 (ALK2), ACVR2A, ACVRL1 (ALK1)
Bone Morphogenetic Protein Receptors​
AMHR2, BMPR1A (ALK3), BMPR1B (ALK6), BMPR2
TGFβ Receptors​
TGFBR1 (ALK5), TGFBR2, TGFBR3
Transcription Factors & Regulators
DLX2, FOS, GSC, HIPK2, ID1, JUN, JUNB, MYC, RUNX1 (AML1), SMAD1 (MADH1), SMAD2 (MADH2), SMAD3 (MADH3), SMAD4 (MADH4), SMAD5 (MADH5), SMAD7, SOX4, STAT1, TGFB1I1, TSC22D1 (TGFB1I4)
SMAD Target Genes
TGFβ / Activin-Responsive​
ATF4, CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), CDKN2B (p15INK4b), COL1A1, COL1A2, DCN, EMP1, FOS, GADD45B, GSC, HERPUD1, IFRD1, IGF1, IGFBP3, IL6, JUN, JUNB, MYC, PDGFB, SERPINE1 (PAI-1), TGFB1I1, TGFBI, TGIF1, TNFSF10 (TRAIL), TSC22D1 (TGFB1I4)
Bone Morphogenetic Protein Responsive​
BGLAP, DLX2, ID1, ID2, JUNB, SOX4, STAT1
Molecules Regulating TGFβ Superfamily Signaling​
BAMBI, BMPER, CDKN2B (p15INK4b), CHRD, ENG (EVI-1), FST, HIPK2, MECOM, NOG, PLAU (UPA), RUNX1 (AML1), SMURF1
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Cell Adhesion Molecules​
BGLAP, ENG (EVI-1), TGFB1I1, TGFBI
Extracellular Matrix (ECM) Structural Constituents​
BGLAP, COL1A1, COL1A2, LTBP1, LTBP2, TGFBI
Cellular & Developmental Processes
Apoptosis​
CDKN1A (p21CIP1, WAF1), CDKN1B (P27KIP1), HIPK2, IGFBP3, INHA, INHBA, STAT1, TGFB1
Embryonic Development​
BMP4, INHBA, MECOM, SMAD3 (MADH3), SMURF1
Muscle Development​
DCN, IGF1, SMAD3 (MADH3)
Neurogenesis​
DLX2, INHA, INHBA, NOG
Reproduction​
AMH, AMHR2, FST, INHA, INHBA, INHBB
Skeletal Development​
BGLAP, BMP1, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMPR2, CHRD, COL1A1, COL1A2, IGF1, INHA, INHBA, NOG
Gene Resource List
Array Layout for PCR Plates
File Size: 153.06 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.2 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Certificates of Analysis (1)
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