GeneGlobe ID: UPHS-093Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human Hepatotoxicity

QuantiNova LNA Probe PCR Focus Panel
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Product Specification

Target List
Cholestasis
ABCB1 (MDR1, PGY1), ABCB4, ABCC2 (MRP2, cMOAT), ABCC3 (MRP3, MOAT-D), ATP8B1, ICAM1, PDYN, RDX, SLC51A
Steatosis
Up-Regulated in Steatosis​
CD36, FASN, LPL, SCD
Down-Regulated in Steatosis​
PPARA, SREBF1
Phospholipidosis
Up-Regulated in Phospholipidosis​
ASAH1, FABP1, HPN, LSS, MRPS18B, S100A8, SERPINA3, WIPI1
Down-Regulated in Phospholipidosis​
SLC2A3, TAGLN
Regulated in Phospholipidosis​
ABCB1 (MDR1, PGY1), TIMM10B
Hepatotoxicity
Up-Regulated in Hepatotoxicity​
ALDOA, APEX1, BTG2, CASP3, CCNG1, CRYL1, DDIT4L (REDD2), DNAJB11, DNAJC3, GADD45A, GCLC, GSR, HMOX1, HYOU1, KRT18, KRT8, NQO1, PLA2G12A, SLC17A3, TXNRD1, YRDC
Down-Regulated in Hepatotoxicity​
AVPR1A, BHMT, CA3, CXCL12 (SDF1), CYP1A2, FADS1, FMO1, HAO2, IGFALS, MBL2, RB1, THRSP
Regulated in Hepatotoxicity​
ABCB11, MAOB, PYGL, TIMM10B
Nongenotoxic Hepatocarcinogenicity
Up-Regulated in Nongenotoxic Hepatocarcinogenicity​
ALDOA, APEX1, BTG2, CCNG1, CDKN1A (p21CIP1, WAF1), DDX39A, KRT18, KRT8, MRPS18B, TXNRD1
Necrosis
Up-Regulated in Necrosis​
CD68, CEMIP2, COL4A1, IL6ST (GP130), IPO4, MAP3K6, NUS1, OSMR, PSME3, SERPINE1 (PAI-1), SKIL, SLC39A6
Down-Regulated in Necrosis​
CDC14B, EMC9, FAM214A, L2HGDH, LGR5, MCM10, MLXIPL, RHBG
Regulated in Necrosis​
CDKN1A (p21CIP1, WAF1), DDX39A
Gene Resource List
Array Layout for PCR Plates
File Size: 154.08 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 154.22 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Safety Data Sheets (1)
Certificates of Analysis (1)