GeneGlobe ID: UPHS-160Z | Cat. No.: 249955 | QuantiNova LNA Probe PCR Focus Panels

QuantiNova LNA Probe PCR Focus Panel Human IL6/STAT3 Signaling Pathway

QuantiNova LNA Probe PCR Focus Panel
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Product Specification

Target List
IL6 / STAT3 Signaling
STAT3 Activators​
CXCL12 (SDF1), EGFR (ERBB1), IL10, IL11, IL17A, IL21, IL23A, IL6
Cell Surface Receptors​
CD4, CD40 (TNFRSF5), CD80, CSF3R (GM-CSFR), CXCR4, FAS, IL18R1, IL1R1, IL2RA (CD25), IL6R, IL6ST (GP130), LIFR, OSMR, TNFRSF10B (DR5), TNFRSF1A (TNFR1), TNFRSF1B
Signaling Upstream of IL6 / STAT3​
AKT1, JAK2, JAK3, MAP2K1, MAPK1 (ERK2), MAPK14 (p38ALPHA), MAPK3 (ERK1), MAPK8 (JNK1), MTOR, MYC, PIAS3, RAC1, SOCS1, SOCS3, SRC, TYK2
Signaling Downstream of IL6 / STAT3​
BAX, BCL2, CDC25A, CDKN1A (p21CIP1, WAF1), HGF, MET, PIM1, STAT3
IL6 / STAT3 Signaling Target Genes​
CCL2 (MCP-1), CCL5 (RANTES), CD80, CEBPD, CXCL10 (INP10), CXCL12 (SDF1), CXCL8 (IL8), IL10, IL11, IL12A, IL17A, IL1B, IL21, IL6, MYC, SOCS3
Cytokines
CCL2 (MCP-1), CCL3 (MIP-1A), CCL4 (MIP-1B), CCL5 (RANTES), CD40LG, CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), CXCL10 (INP10), CXCL12 (SDF1), CXCL8 (IL8), FASLG (TNFSF6), IL10, IL11, IL13, IL15, IL17A, IL18, IL1A, IL1B, IL2, IL21, IL22, IL23A, IL3, IL4, IL5, IL6, IL7, IL9, LIF, LTA (TNFB), OSM, TNF, TNFSF10 (TRAIL), TNFSF11 (RANKL)
NFκB Signaling
IKBKB (IKKβ), NFKB1, NFKBIA (IκBα, MAD3), RELA, TLR4
Gene Resource List
Array Layout for PCR Plates
File Size: 152.94 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 153.08 KBLanguage: English

Resources

Kit Handbooks (1)
QuantiNova LNA Probe PCR Handbook
Quick-Start Protocols (1)
Certificates of Analysis (1)
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