Target List
Th1 Genes
Th1 Markers​
CCR5, CXCR3, IFNG, STAT4, TBX21
Th1 Immune Response​
CCR2, CD80, EBI3, IL12B, IL18, IL1RL1 (ST2), IL27, IL27RA, IL4R (CD124), SLC11A1, SOCS5, TLR4, TLR6, TNFSF4 (OX40L), VEGFA
Other Th1-Related Genes​
CD28, CD40LG, CSF2 (GM-CSF), HAVCR2, IL12RB2, IL18R1, IL2, IL2RA (CD25), IRF1, SOCS1, STAT1, TNF
Cell-Mediated Immunity
BCL6, CD27 (TNFRSF7), CD28, CD40LG, IFNG, IL10, IL12B, IL2, IL27RA, IL4, IL7R, LTA (TNFB), PTPRC, SLC11A1, STAT6, TBX21, TLR4, TNF, TNFSF4 (OX40L)
Th2 Genes
Th2 Markers​
CCR4, GATA3, IL13, IL25, IL2RA (CD25), IL4, IL4R (CD124), IL5, STAT6
Th2 Immune Response​
BCL6, CCR2, CD86, IL10, IL18, IL27RA, IL6, SOCS5, TNFSF4 (OX40L)
Other Th2-Related Genes​
CCL11 (Eotaxin), CCL5 (RANTES), CCL7 (MCP-3), CCR3, CEBPB, GFI1, PTGDR2 (CRTH2, GPR44), ICOS, IL13RA1, IL1R1, IL9, IRF4, JAK1, MAF, NFATC1, NFATC2, PCGF2
Humoral Immunity
CD28, EBI3, IFNG, IL6, IL7, LTA (TNFB), TNF
CD4+ T-Cell Markers
CD27 (TNFRSF7), CD4, CD40LG, CD80, CD86, CREBBP (CBP), CTLA4, FASLG (TNFSF6), IL15, IL6, IL6R, IL7, JAK2, LAG3, LAT, MAPK8 (JNK1), PTPRC, TGFB3, TNFRSF8, TNFRSF9, TNFSF4 (OX40L), TYK2, YY1
Other Inflammatory Response Genes
IL24, JAK2, LTA (TNFB), SPP1
Other Immune Response Genes
IL3, SFTPD