Wsb2 Gene Summary [Rat]

Predicted to be involved in protein polyubiquitination. Orthologous to human WSB2 (WD repeat and SOCS box containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Wsb2
Official Name
WD repeat and SOCS box-containing 2 [Source:RGD Symbol;Acc:1359599]
Ensembl ID
ENSRNOG00000001135
Bio databases IDs NCBI: 288692 Ensembl: ENSRNOG00000001135
Aliases WD repeat and SOCS box-containing 2
Synonyms SBA2, Swip2, WD repeat and SOCS box-containing 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wsb2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SOCS box
  • WD40 repeats
  • WD domain, G-beta repeat
  • SOCS
  • WD40
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • chronic sinusitis
regulated by
regulates
role in cell
  • growth
  • thenoyltrifluoroacetone sensitivity
  • degradation in
  • ubiquitination in
  • stabilization in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Wsb2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein polyubiquitination
  • intracellular signal transduction

Cellular Component

Where in the cell the gene product is active
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.