Neurl2 Gene Summary [Rat]
Predicted to be involved in intracellular signal transduction and protein ubiquitination. Predicted to act upstream of or within sarcomere organization. Predicted to be located in muscle tendon junction. Predicted to be part of VCB complex. Orthologous to human NEURL2 (neuralized E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Neurl2 |
| Official Name | neuralized E3 ubiquitin protein ligase 2 [Source:RGD Symbol;Acc:1306409] |
| Ensembl ID | ENSRNOG00000015797 |
| Bio databases IDs | |
| Aliases | neuralized E3 ubiquitin protein ligase 2 |
| Synonyms | C20orf163, Neur2, neuralized E3 ubiquitin protein ligase 2, OZZ, OZZ-E3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Neurl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SOCS box
- Neuralized
- SPRY domain
- SOCS
- protein binding
- domain in neuralized proteins
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- cell-matrix adherens junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Neurl2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular signal transduction
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol