Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Hotspot Coverage
AKT1, APC, BRAF, CTNNB1, DPYD, EGFR (ERBB1), FBXW7, GNAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET, SMAD4 (MADH4), UGT1A1
Whole Coding Coverage
ERBB2 (HER-2, NEU), KRAS, TP53 (p53)
Adenocarcinomas
APC, BRAF, CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), FBXW7, GNAS, KRAS, MAP2K1, NRAS, RET, SMAD4 (MADH4), TP53 (p53)
Metastatic Colorectal Cancers
AKT1, BRAF, CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET
Other Colorectal Cancer Genes
BRAF, CTNNB1, DPYD, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET, UGT1A1