Target List
Hotspot Coverage
AKT1, APC, BRAF, CTNNB1, DPYD, EGFR (ERBB1), FBXW7, GNAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET, SMAD4 (MADH4), UGT1A1
Whole Coding Coverage
ERBB2 (HER-2, NEU), KRAS, TP53 (p53)
Adenocarcinomas
APC, BRAF, CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), FBXW7, GNAS, KRAS, MAP2K1, NRAS, RET, SMAD4 (MADH4), TP53 (p53)
Metastatic Colorectal Cancers
AKT1, BRAF, CTNNB1, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET
Other Colorectal Cancer Genes
BRAF, CTNNB1, DPYD, EGFR (ERBB1), ERBB2 (HER-2, NEU), KRAS, MAP2K1, NRAS, PIK3CA (p110-alpha), RET, UGT1A1