Boll Gene Summary [Mouse]

Predicted to enable identical protein binding activity; mRNA 3'-UTR binding activity; and translation activator activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization and positive regulation of translational initiation. Predicted to act upstream of or within meiotic cell cycle. Predicted to be active in cytoplasm. Is expressed in central nervous system; germ cell of gonad; and sensory organ. Orthologous to human BOLL (boule homolog, RNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Boll
Official Name
boule homolog, RNA binding protein [Source:MGI Symbol;Acc:MGI:1922638]
Ensembl ID
ENSMUSG00000025977
Bio databases IDs NCBI: 75388 Ensembl: ENSMUSG00000025977
Aliases boule homolog, RNA binding protein
Synonyms 4930554P13Rik, 4930597B14RIK, BOULE, boule homolog, RNA binding protein, LOC108348134, RGD1559527
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Boll often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • translation activator
  • protein binding
  • identical protein binding
  • translation regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • cerebral aneurysm
  • azoospermia
  • asthma
  • rheumatoid arthritis
  • aspermatogenesis
  • idiopathic dilated cardiomyopathy
regulated by
  • 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • methylnitrosourea
regulates
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Boll gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of translational initiation
  • 3'-UTR-mediated mRNA stabilization
  • meiotic cell cycle
  • spermatogenesis
  • cell differentiation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • translation activator activity
  • mRNA 3'-UTR binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.