Serf2 Gene Summary [Mouse]

Predicted to be involved in protein destabilization. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including brain; endocrine gland; genitourinary system; oral epithelium; and respiratory system. Orthologous to human SERF2 (small EDRK-rich factor 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Serf2
Official Name
small EDRK-rich factor 2 [Source:MGI Symbol;Acc:MGI:1337041]
Ensembl ID
ENSMUSG00000074884
Bio databases IDs NCBI: 378702 Ensembl: ENSMUSG00000074884
Aliases small EDRK-rich factor 2
Synonyms 4F5REL, FAM2C, H4F5REL, Hero7, HsT17089, m4F5rel, Msmac1l, small EDRK-rich factor 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • 4F5 protein related disordered region

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • liver cancer
  • prostate cancer
  • hepatocellular carcinoma
  • developmental delay
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Serf2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein destabilization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.