Rnf166 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including brain; hemolymphoid system gland; liver; lung; and spinal cord. Orthologous to human RNF166 (ring finger protein 166). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnf166 |
| Official Name | ring finger protein 166 [Source:MGI Symbol;Acc:MGI:1915968] |
| Ensembl ID | ENSMUSG00000014470 |
| Bio databases IDs | |
| Aliases | ring finger protein 166 |
| Synonyms | 1110031E24Rik, ring finger protein 166, Zfp313l |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf166 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Drought induced 19 protein (Di19), zinc-binding
- C2HC Zing finger domain
- Ring finger
- zinc finger of C3HC4-type, RING
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger domain
- protein binding
- RING-H2 zinc finger domain
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rnf166 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- protein polyubiquitination
- innate immune response
- ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding