FAIM Gene Summary [Human]
The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Details
| Type | Retained Intron |
| Official Symbol | FAIM |
| Official Name | Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703] |
| Ensembl ID | ENSG00000158234 |
| Bio databases IDs | |
| Aliases | Fas apoptotic inhibitory molecule |
| Synonyms | FAIM1, Faim-S, Fas apoptotic inhibitory molecule, FLJ10582 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FAIM often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Fas apoptotic inhibitory molecule (FAIM1)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- liver cancer
- hepatocellular carcinoma
role in cell
- phosphorylation in
- autophagy in
- apoptosis
- cell death
- outgrowth
- production in
- outgrowth in
- autoubiquitination in
- association in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FAIM gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding