Ugt2b1 Gene Summary [Mouse]

Enables glucuronosyltransferase activity. Acts upstream of or within protein heterooligomerization and protein homooligomerization. Part of protein-containing complex. Orthologous to several human genes including UGT2B4 (UDP glucuronosyltransferase family 2 member B4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ugt2b1
Official Name
UDP glucuronosyltransferase 2 family, polypeptide B1 [Source:MGI Symbol;Acc:MGI:1919023]
Ensembl ID
ENSMUSG00000035836
Bio databases IDs NCBI: 71773 Ensembl: ENSMUSG00000035836
Aliases UDP glucuronosyltransferase 2 family, polypeptide B1
Synonyms 1300012D20Rik, 2B1, Udp glucuronosyl transferase, UDP glucuronosyltransferase 2 family, polypeptide B1, Udpgtr2, Ugt2b17
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ugt2b1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • glycosyltransferase family 1 and related proteins with GTB topology
  • glycosyltransferase, MGT family
  • enzyme
  • UDP-glucoronosyl and UDP-glucosyl transferase
  • glucuronosyltransferase

Pathways

Biological processes and signaling networks where the Ugt2b1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • phenobarbital
  • myclobutanil
  • methylprednisolone
  • ursodeoxycholic acid
  • 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene
  • triadimefon
  • 1,7-phenanthroline
  • GPD1
  • SLC25A13
  • NR1I3
regulates
  • estrogen
  • diclofenac
  • diclofenac acyl glucuronide
  • UDP-glucuronic acid
  • xenobiotic
  • testosterone
  • diphenyl

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • microsome
  • outer nuclear membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.