Rps15 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in positive regulation of signal transduction by p53 class mediator and ribosome biogenesis. Part of cytosolic small ribosomal subunit. Orthologous to human RPS15 (ribosomal protein S15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps15 |
| Official Name | ribosomal protein S15 [Source:MGI Symbol;Acc:MGI:98117] |
| Ensembl ID | ENSMUSG00000063457 |
| Bio databases IDs | |
| Aliases | ribosomal protein S15 |
| Synonyms | ribosomal protein S15, RIG, S15, uS19 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- enzyme inhibitor activity
- rpsS
- protein binding
- enzyme regulator activity
- Ribosomal protein S19
Pathways
Biological processes and signaling networks where the Rps15 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- leiomyoma
- leiomyomatosis
regulates
- TP53
- CDKN1A
- let-7 (includes others)
- mir-10 (includes others)
- mir-8 (includes others)
- mir-30 (includes others)
- MIR29B
- mir-423
- mir-192 (includes others)
- mir-28 (includes others)
role in cell
- proliferation
- expression in
- accumulation in
- cell death
- stabilization in
- synthesis in
- processing in
- ubiquitination in
- translation in
- G2 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- ribosome
- cytosol
- nucleoplasm
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit export from nucleus
- cytoplasmic translation
- ribosomal small subunit biogenesis
- osteoblast differentiation
- rRNA processing
- ribosomal small subunit assembly
- translation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosolic ribosome
- focal adhesion
- cytoplasm
- cytosolic small ribosomal subunit
- membrane
- cytosol
- synapse
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- RNA binding
- structural constituent of ribosome