TRAPPC6A Gene Summary [Human]

This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Details

Type
Protein Coding
Official Symbol
TRAPPC6A
Official Name
trafficking protein particle complex 6A [Source:HGNC Symbol;Acc:HGNC:23069]
Ensembl ID
ENSG00000007255
Bio databases IDs NCBI: 79090 Ensembl: ENSG00000007255
Aliases trafficking protein particle complex 6A, trafficking protein particle complex subunit 6A
Synonyms 1810073E21RIK, 4930519D19Rik, LOC686599, mhyp, RGD1309160, trafficking protein particle complex 6A, trafficking protein particle complex subunit 6A, TRS33
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRAPPC6A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Transport protein particle (TRAPP) component
  • protein binding
  • Bet3-like domains of TRAPP

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
role in cell
  • activation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TRAPPC6A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport
  • COPII vesicle coating

Cellular Component

Where in the cell the gene product is active
  • TRAPP complex
  • trans-Golgi network
  • cis-Golgi network
  • cytoplasm
  • cytosol
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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